The problem of validation criteria for developing ion-selective membrane electrodes for the analysis of pharmaceuticals arises from the connection between the reliability of ion-selective membrane electrodes construction and the reliability of the analytical information. Liquid membrane selective electrodes are more suitable for validation than the solid variety. The influence of the stability of ion pair complexes from the membrane on various parameters (e.g. response, limit of detection, and selectivity) is discussed. Validation criteria are proposed. © 2005 Springer-Verlag Berlin Heidelberg.
CITATION STYLE
Stefan, R. I., & Aboul-Enein, H. Y. (2005). Validation criteria for developing ion-selective membrane electrodes for analysis of pharmaceuticals. In Validation in Chemical Measurement (pp. 73–75). Springer Berlin Heidelberg. https://doi.org/10.1007/3-540-27034-5_13
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