Tofacitinib for rheumatoid arthritis

Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows: To evaluate the benefits and harms of tofacitinib for the treatment of rheumatoid arthritis. Our PICO question is as follows: Population: Adult patients with rheumatoid arthritis. Intervention: Tofacitinib alone or combined with any DMARD. Comparison: Placebo or DMARD. Outcomes: Efficacy, radiographic, patient-reported and safety outcomes.