Particular clinical characteristics of segmental vitiligo

Abstract

In 1977, Koga performed a sweat-secretion stimulation test using physiostigmine and accordingly reclas-sified vitiligo into nonsegmental type (Type A), and segmental type (Type B) [6]. He proposed that the non-segmental type results from immunologic mechanisms, while segmental type results from dysfunction of the sympathetic nervous system in the affected skin (see below, Gauthier and Benzekri). Following are personal observations, which suggest alternative hypotheses. © 2010 Springer-Verlag Berlin Heidelberg.