Assessment of the pulse wave variability for a new non-invasive device

Abstract

The main motivation of this work was to provide a valid contribution for the assessment of the cardiovascular condition by the analysis of several Arterial Pressure Waveform (APW) parameters collected by a new non-invasive device. Three sets of recordings for the carotid pressure waveform at left and right carotid arteries were performed, under standardized conditions, in 20 volunteers by three trained operators. The mean of the inter-operator differences were higher for the right artery, comparatively to the left artery. In this case, an Augmentation Index (AIx) value of −2.31 ± 7.29 % and a Systolic Wave Transit Time (SWTT) value of −12.94 ± 31.46 ms were observed, which are higher than the left measurements, 0.94 ± 7.52 % and −2.96 ± 22.67 ms, respectively. Intra-operator differences were calculated for each of the three sets of measurements and showed good reproducibility. The pulse-by-pulse variability analysis gives very good markers for the Left Ventricular Ejection Time (LVET), Dicrotic Wave Amplitude (DWA), Reflection Wave Amplitude (RWA), Coefficient of Variation (CV) < 10 %, and satisfactory values for the AIx (CV< 30 %). The SWTT and Reflected Wave Transit Time (RWTT) also presented satisfactory results (10 %