Dopamine neurons of the substantia nigra compacta (SNc) and ventral tegmental area (VTA) are critical components of the neuronal machinery to control emotion and movement in mammals. The slow and gradual death of these neurons as seen in Parkinson’s disease has triggered a large investment in research toward unraveling the molecular determinants that are used to generate these neurons and to get an insight in their apparent selective vulnerability. Here, I set out to summarize the current view on the molecular distinctions that exist within this mesodiencephalic dopamine (mdDA) systemand elaborate on themolecular programming that is responsible for creating such diversity.
CITATION STYLE
Smidt, M. P. (2017). Molecular programming of mesodiencephalic dopaminergic neuronal subsets. Frontiers in Neuroanatomy, 11. https://doi.org/10.3389/fnana.2017.00059
Mendeley helps you to discover research relevant for your work.