Advances in the techniques for the prediction of microRNA targets

39Citations
Citations of this article
92Readers
Mendeley users who have this article in their library.

Abstract

MicroRNAs (miRNAs) are small, non-coding, endogenous RNA molecules that play important roles in a variety of normal and diseased biological processes by post-transcriptionally regulating the expression of target genes. They can bind to target messenger RNA (mRNA) transcripts of protein-coding genes and negatively control their translation or cause mRNA degradation. miRNAs have been found to actively regulate a variety of cellular processes, including cell proliferation, death, and metabolism. Therefore, their study is crucial for the better understanding of cellular functions in eukaryotes. To better understand the mechanisms of miRNA: mRNA interaction and their cellular functions, it is important to identify the miRNA targets accurately. In this paper, we. © 2013 by the authors; licensee MDPI, Basel, Switzerland.

Author supplied keywords

Cite

CITATION STYLE

APA

Zheng, H., Fu, R., Wang, J. T., Liu, Q., Chen, H., & Jiang, S. W. (2013). Advances in the techniques for the prediction of microRNA targets. International Journal of Molecular Sciences. MDPI AG. https://doi.org/10.3390/ijms14048179

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free