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Questions about how and why tissue regeneration occurs capture the attention of countless biologists, biomedical engineers, and clinicians. Regenerative capacity differs greatly across organs and organisms, and a spectrum of model systems with different technical advantages and regenerative strategies are studied. Several key issues common to natural regenerative events are receiving new attention from improving models and approaches, including: the determination of regenerative capacity; the importance of stem cells, dedifferentation and transdifferentiation; how regenerative signals are initiated and targeted; and the mechanisms that control regenerative proliferation and patterning. Regeneration




Poss, K. D. (2010, October 14). Advances in understanding tissue regenerative capacity and mechanisms in animals. Nature Reviews Genetics. https://doi.org/10.1038/nrg2879

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