Determination of the bioimpedance analysis parameters in dengue patients using the self organizing map

Abstract

This paper presents the determination of the bioimpedance analysis parameters in dengue infection using the self organizing map. The self organizing map (SOM) was used for visualizing, understanding and exploring the significant bioimpedance analysis (BIA) parameters that can distinguish between dengue patients and the healthy patients. Database of 329 data set (203 females and 126 males) were used in this study. The investigation was conducted on the day of defervescence of fever. The BIA parameters, which are comprised of Resistance, Reactance, Phase Angle, Body Capacitance, Body Cell Mass, Extracellular Mass, Fat Mass, Body Mass Index, Basal Metabolic Rate, Total Body Water, Intracellular Water, Extracellular Water, Lean body mass, and weight are used. Three bars of training were conducted. The first training was conducted using all the data. The best map size was found as 100 units. Second training was conducted based on the female's data. The best map size was found as 72 units. Finally, 70 units SOM was obtained when the male's data was used. Moreover, significant results were found by visualizing the three trained maps. The SOM showed that the reactance is significantly low in dengue patients when the all data was used. However, when the data was analyzed separately for females and males, the SOM showed that the Intracellular Water is significantly low while the ratio of the Extracellular Water and Intracellular Water are significantly high in both males and females. Moreover, the SOM showed that the reactance is significantly high while the ratio of the Extracellular Mass and Body Cell Mass is significantly low for females. © 2008 Springer-Verlag.