HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases

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Abstract

This letter demonstrates the potential of novel cryptic proteins resulting from TAR DNA-binding protein 43 (TDP-43) dysfunction as markers of TDP-43 pathology in neurodegenerative diseases.

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Calliari, A., Daughrity, L. M., Albagli, E. A., Castellanos Otero, P., Yue, M., Jansen-West, K., … Petrucelli, L. (2024, December 1). HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases. Molecular Neurodegeneration. BioMed Central Ltd. https://doi.org/10.1186/s13024-024-00718-8

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