Antimicrobial resistance in microbes: Mode of action of tolc like protein and their mechanism of regulating stress resistance and physiology

Abstract

Although Acinetobacter baumannii is considered the most common nosocomial species that cause severe infections, only few studies have demonstrated the physiological role of outer membrane proteins (OMPs) and its pathogenic potential. Here, we discuss the functions of putative outer membrane protein in physiology and multidrug resistance. The abuO like genes were functionally characterized in genetically distinct A. baumannii obtained from a tertiary medical center in India. This sequel study provides evidence for the strain non-specific unanimous function of abuO in stress response and antimicrobial resistance in A. baumannii.