Role of gender and age on early mortality after coronary artery bypass graft in different hospitals: Data from a national administrative database

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Abstract

The aim of this study is to evaluate the effect of gender and age on outcome following coronary surgery in several hospitals enrolled in a national quality assessment program. Patients undergoing isolated coronary artery bypass graft (CABG) during 2003-2005 in Italy were included in the study (n=74,577). The outcome measure was 30-day in-hospital mortality. Comorbidities recorded during previous and current hospitalizations were used to define patients' health status and to build the adjustment model. The interaction term (genderhospital) was introduced into the model to test the effect modification of gender; if present, gender specific models were analyzed to test the effect modification of age. A significant effect modification by gender was found in 39 hospitals; the adjusted odds ratios (AdjORs) showed significant increased risk for females (AdjORs ranging from 3.7 to 21.6). In three of these hospitals a significant increased risk was found for older age (AdjORs for elderly patients ranging from 8.1 to 14.6). Two hospitals showed a significant excess risk for patients ≥75 years (AdjORs=6.6 and 13.8). The technical aspects of surgery could account for the excess risk found in female patients; differences in the entire care process (intraoperative and postoperative management) could explain the variations in outcome among elderly patients. © 2010 Published by European Association for Cardio-Thoracic Surgery.

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Maraschini, A., Seccareccia, F., D’Errigo, P., Rosato, S., Badoni, G., Casali, G., & Musumeci, F. (2010). Role of gender and age on early mortality after coronary artery bypass graft in different hospitals: Data from a national administrative database. Interactive Cardiovascular and Thoracic Surgery, 11(5), 537–542. https://doi.org/10.1510/icvts.2010.233296

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