The aim of this study was to investigate the possible associations between insertion/deletion (ID) polymorphism in angiotensin-converting enzyme (ACE) (dbSNP rs 4646994) with the food intake and body composition in the Czech non-obese, obese and extremely obese populations. A total of 453 various-weighted individuals were enrolled in the study and were according to their BMI assigned into following subgroups, such as obese (30 ≤ BMI<40), morbidly obese (BMI≥40) and nonobese (20 <210, 210-260, and >260 g of carbohydrates/day, respectively. Based on our findings, the ID ACE polymorphism could represent a gene modulator of carbohydrate intake in morbidly obese Czech population; the strong significant effect of DD genotype was observed in the phenotypes of extreme obesity with the highest carbohydrate intake. © Springer-Verlag 2009.
CITATION STYLE
Bienertova-Vasku, J., Bienert, P., Sablikova, L., Slovackova, L., Forejt, M., Piskackova, Z., … Vasku, A. (2009). Effect of ID ACE gene polymorphism on dietary composition and obesity-related anthropometric parameters in the Czech adult population. Genes and Nutrition, 4(3), 207–213. https://doi.org/10.1007/s12263-009-0130-9
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