Abstract
Eight eyes of 7 patients with fungal disease received intravenous injections of 150 to 300 mg micafungin, and samples of blood, cornea, retina-choroid, aqueous humor, and vitreous humor were collected. The micafungin levels in all collected samples exceeded the MICs; however, the levels in the vitreous and aqueous humors were lower. Our findings suggest that intravenous micafungin should be given in combination with intravitreal antifungal agents after vitrectomy in severe cases of intraocular fungal diseases. © 2013 American Society for Microbiology. All rights reserved.
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
Cite
CITATION STYLE
Mochizuki, K., Sawada, A., Suemori, S., Kawakami, H., Niwa, Y., Kondo, Y., … Kishinoi, S. (2013). Intraocular penetration of intravenous micafungin in inflamed human eyes. Antimicrobial Agents and Chemotherapy, 57(8), 4027–4030. https://doi.org/10.1128/AAC.02300-12
Readers over time
Readers' Seniority
Readers' Discipline
