Antifibrinolytic Drugs (Aminocaproic Acid and Tranexamic Acid): Treatment Perspectives for Dental Surgery

Abstract

The purpose of the review was to evaluate the risks and benefits of antifibrinolytic drugs, aminocaproic acid and tranexamic acid, with respect to dental surgery. The literature supports the utilization of antifibrinolytic drugs particularly with regard to hemophilia and other bleeding dyscrasias. Systemic therapy has potential risks, although blood studies allow for the safe utilization of antifibrinolytics. The use of topical antifibrinolytic drugs demonstrates benefit without significant risk.