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A new synthesis of a potent cancer chemopreventive agent, 13-oxo-15,16-dinorlabda-8(17),11E-dien-19-oic acid from trans-communic acid

Chemical and Pharmaceutical Bulletin (2002) 50(12) 1625-1629
DOI: 10.1248/cpb.50.1625
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Abstract

The first synthesis of a labdane diterpenoid, (-)-13-oxo-15,16-dinorlabda- 8(17),11E-dien-19-oic acid [(-)-1a], isolated from the stem bark of Thuja standishii (GORD.) CARR., from the major component trans-communic acid (3a) is described. © 2002 Pharmaceutical Society of Japan.

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Katoh, T., Tanaka, R., Takeo, M., Nishide, K., & Node, M. (2002). A new synthesis of a potent cancer chemopreventive agent, 13-oxo-15,16-dinorlabda-8(17),11E-dien-19-oic acid from trans-communic acid. Chemical and Pharmaceutical Bulletin, 50(12), 1625–1629. https://doi.org/10.1248/cpb.50.1625

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