New prenylated C6-C3 compounds from the twigs of Illicium anisatum

Abstract

Two new prenylated C6-C3 compounds, cycloillicinone (1) and 4-allyl-2-methoxy-6-(2-methylbut-3-en-2-yl)phenol (2), were isolated from the twigs of Illicium anisatum, and their structures were determined by 2D-NMR methods. Cycloillicinone (1) is a unique prenylated C6-C 3 that is appended with an additional geranyl unit. Compound 2 was found to show moderate neurite-outgrowth promoting activity in primary cultured rat cortical neurons at a concentration of 10 μM. © Pharmaceutical Society of Japan.