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A synthetic retinoid Am80 (tamibarotene) rescues the memory deficit caused by scopolamine in a passive avoidance paradigm

Biological and Pharmaceutical Bulletin (2004) 27(11) 1887-1889
DOI: 10.1248/bpb.27.1887
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Abstract

Memory deficit in rats treated with scopolamine was rescued by several synthetic retinoids, RAR-ligands (Am80, Am555S, Tp80) and an RXR-ligand (HX630). These results may have implications for the treatment of Alzheimer's disease, age-related dementia, Parkinson's disease, and other neurological disorders. © 2004 Pharmaceutical Society of Japan.

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Shudo, K., Kagechika, H., Yamazaki, N., Igarashi, M., & Tateda, C. (2004). A synthetic retinoid Am80 (tamibarotene) rescues the memory deficit caused by scopolamine in a passive avoidance paradigm. Biological and Pharmaceutical Bulletin, 27(11), 1887–1889. https://doi.org/10.1248/bpb.27.1887

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