Application of solvation equations to chemical and biochemical processes

Abstract

Two solvation equations that can be used either as LSERs or as QSARs have been applied to various processes that involve transfer of a series of solutes from the gas phase to a condensed phase or transfer of a series of solutes from one condensed phase to another. In the former class, the processes include gas-liquid chromatography, gas-solid chromatography, the solubility of gases and vapours in polymers and organic solvents, and upper respiratory tract irritation in mice. The latter class includes water-octanol and other partitions, the inhibition of firefly luciferase enzyme by aqueous nonelectrolytes, and general anaesthesia. © 1993 IUPAC.