Methadone Extraction by Modified Quechers and Liquid-Liquid Extraction from Post-Mortem Urine by GC-MS

Abstract

Background: Methadone abuse in drug addiction centers and increased methadone consumption among addicts is a new cause of mortality due to substance abuse in forensic medicine. The usual method of extracting urine from corpses in most legal centers is a long and costly method of liquid-liquid extraction, which in addition to the high consumption of solvents and environmental contamination causes severe damage to the column of laboratory analysis devices. As a result, QuEChERS extraction method was proposed as an easy, fast, cheap and green way.