Precision and Accuracy of Thyroid Dysfunction Questionnaire (TDQ) for Hyperthyroidism Screening in Childbearing Age Women

Abstract

Background: Community-based case finding efforts of hyperthyroidism rather not to do, but constrained because accurate markers measurements using hormones. TDQ as a screening instrument which meets several criteria diagnostic tests, provide more convenience for the patient, cheaper, easier and simpler. This study aimed to determine the precision and accuracy of diagnostic test of hyperthyroidism screening in childbearing age women. Subjects and Method: The study was a diagnostic study with cross sectional design. It conducted in Prambanan, Sleman, Yogyakarta. The sample consisted of 112 randomly selected of childbearing age women.Clinical symptoms of hyperthyroidism were measured using the TDQ, thyroid status measured by thyroid stimulating hormone (TSH) and free thyroxin (FT4). TDQ diagnostic precision and accuracy were tested using the percent agreement (PA), Kappa coefficient, sensitivity (Se), specificity (Sp), LR (+), LR (-