Nanomedicine: Size-related drug delivery applications, including periodontics and endodontics

Abstract

In this chapter, we discuss polymer- and liposome-based nanocarriers used in the delivery of bioactive molecules, from drugs to proteins. The focus is on the enhancements in efficacy of bioactive molecules when nanotechnology is used for delivering them. The perspective centres around commercial and clinical successes and a rationalization of these successes. Microparticulate systems are also discussed in relation to their nano-counterparts, and the advantages of nano size are emphasized in relevant applications. In general, the main application of nanocarriers is in cancer therapy; however, with the ability to programme sustained release of bioactive molecules from certain types of nanoparticles, other applications in ocular, cardiovascular and periodontic/endodontic therapy may be possible.