Neural signature of event-related N200 and P300 modulation in parietal lobe during human response inhibition

Abstract

Response inhibition is a process of motor control and related to the suppression of the action. The role of inhibition in many studies remains an issue of debate, most researchers nevertheless agree that some sort of inhibition mechanism is involved in the deliberate cessation of a motor response. Therefore, stop-signal task has been designed to investigate the response inhibition. Other aspects also encourage the importance of this study, because deficits in response inhibition is an essence in a variety of neurological disorders such as schizophrenia and attention deficit hyperactivity disorder (ADHD). The aim of present study is to examine the brain modulation of left and right-hand response inhibitions with electroencephalography (EEG). The results indicate response inhibition related neural signatures including the N200 and P300 waves in the frontal, central and parietal regions. This work accomplishes that the independent nature of the inhibitory control of the left-and right-hand.