Antioxidant status and muscle cell leakage during endurance exercise.

74Citations
Citations of this article
39Readers
Mendeley users who have this article in their library.

Abstract

Antioxidant status of 35 endurance horses was studied during an 80 (OD80) or 160 km (OD160) race. Packed cell volume (PCV), total plasma protein (TPP), plasma ascorbic acid (VIT C), plasma alpha-tocopherol (VIT E) and erythrocyte glutathione (GSH) concentrations, erythrocyte glutathione peroxidase (GPX), plasma aspartate aminotransferase (AST) and plasma creatine kinase (CK) activities were measured at 0, 40, 80 km and 60 min of recovery (REC) at OD80, and 0, 64, 106, 142, 160 km and REC at OD160. In both races, no changes were found in plasma VIT E concentration, but VIT C and GSH concentrations decreased (P<0.05), and mean GPX, AST and CK activities increased from 0 km (P<0.05). Indices of muscle cell leakage (plasma AST and CK) were correlated (r = 0.36 to 0.67; P<0.03) with indices of antioxidant status (VIT C, GSH and GPX). Associations between increased muscle leakage and decreased antioxidant status may, in part, reflect oxidative stress and suggest the testing of antioxidant supplements in endurance horses to improve performance and welfare.

Cite

CITATION STYLE

APA

Hargreaves, B. J., Kronfeld, D. S., Waldron, J. N., Lopes, M. A., Gay, L. S., Saker, K. E., … Harris, P. A. (2002). Antioxidant status and muscle cell leakage during endurance exercise. Equine Veterinary Journal. Supplement, (34), 116–121. https://doi.org/10.1111/j.2042-3306.2002.tb05402.x

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free