PTEN Germline Mutations in Patients Initially Tested for Other Hereditary Cancer Syndromes: Would Use of Risk Assessment Tools Reduce Genetic Testing?

Abstract

Cite the risk assessment tools available for several hereditary cancer predisposition syndromes. Describe ways in which use of these risk assessment tools can lead to cost savings and decreased time to correct diagnosis. Explain the impact of correct genetic diagnosis on the patient's medical management and on predictive testing for family members.