Influence of hepatitis C virus (HCV) genotypes on HCV recombinant immunoblot assay patterns

Abstract

Ninety-six patients with chronic hepatitis C were studied. A second- generation recombinant immunoblot assay detected anti-NS4 antibodies significantly more often in patients infected by hepatitis C virus genotype 1 than in patients infected by other types. By a third-generation recombinant immunoblot assay, the prevalences of the four antibodies measured did not differ according to the hepatitis C virus genotype.