AML cytogenetics: The complex just got simpler

Abstract

In this issue of Blood, Middeke et al, for the well-regarded Cooperative German Transplant Study Group, report a retrospective analysis in which they demonstrate that a hierarchial classification system for specific cytogenetic abnormalities in acute myeloid leukemia (AML) reveals that patients with abnormal 17p [abnl(17p)] and -5/5q- abnormalities have worse outcomes after allogeneic hematopoietic cell transplantation (HCT).