An Atraumatic Femoral Fracture in a Patient with Rheumatoid Arthritis and Osteoporosis Treated with Denosumab

  • Villiers J
  • Clark D
  • Jeswani T
  • et al.
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Abstract

Osteoporosis is responsible for a significant burden both individually and socially, but is readily treated with antiresorptive agents and mineral supplementation. However, long-term usage of these agents, notably bisphosphonates, is rarely associated with atypical fractures. Denosumab is a monoclonal antibody that reduces osteoclast activity and thus increases bone mineral density. In this case report, we present a 78-year-old woman with a background of rheumatoid arthritis and osteoporosis who presented with an atypical diaphyseal femoral fracture.

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Villiers, J., Clark, D. W., Jeswani, T., Webster, S., & Hepburn, A. L. (2013). An Atraumatic Femoral Fracture in a Patient with Rheumatoid Arthritis and Osteoporosis Treated with Denosumab. Case Reports in Rheumatology, 2013, 1–4. https://doi.org/10.1155/2013/249872

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