Current progress in gene delivery technology based on chemical methods and nano-carriers

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Abstract

Gene transfer methods are promising in the field of gene therapy. Current methods for gene transfer include three major groups: viral, physical and chemical methods. This review mainly summarizes development of several types of chemical methods for gene transfer in vitro and in vivo by means of nano-carriers like; calcium phosphates, lipids, and cationic polymers including chitosan, polyethylenimine, polyamidoamine dendrimers, and poly(lactide-co-glycolide). This review also briefly introduces applications of these chemical methods for gene delivery. © Ivyspring International Publisher.

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Jin, L., Zeng, X., Liu, M., Deng, Y., & He, N. (2014). Current progress in gene delivery technology based on chemical methods and nano-carriers. Theranostics. https://doi.org/10.7150/thno.6914

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