Wilms Tumor: Prognosis Using Microvessel Density

Abstract

Wilms tumor (WT), the most common malignant neoplasm of the kidney in infants and children, is a triphasic tumor that mimics various stages of nephrogenesis, composed of epithelial, blastemal and stromal cells. More than 90% of the cases occur in children less than 6-years of age, mostly between 2 and 5 years. WT has overall survival rates exceeding 90% by the improvement of surgical and anesthetic procedures, and the combination of chemotherapy and radiotherapy.