A Versatile Room‐Temperature Route to Di‐ and Trisubstituted Allenes Using Flow‐Generated Diazo Compounds

  • Poh J
  • Tran D
  • Battilocchio C
  • et al.
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Abstract

A copper‐catalyzed coupling reaction between flow‐generated unstabilized diazo compounds and terminal alkynes provides di‐ and trisubstituted allenes. This extremely mild and rapid transformation is highly tolerant of several functional groups.

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Poh, J., Tran, D. N., Battilocchio, C., Hawkins, J. M., & Ley, S. V. (2015). A Versatile Room‐Temperature Route to Di‐ and Trisubstituted Allenes Using Flow‐Generated Diazo Compounds. Angewandte Chemie, 127(27), 8031–8034. https://doi.org/10.1002/ange.201501538

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