A copper‐catalyzed coupling reaction between flow‐generated unstabilized diazo compounds and terminal alkynes provides di‐ and trisubstituted allenes. This extremely mild and rapid transformation is highly tolerant of several functional groups.
CITATION STYLE
Poh, J., Tran, D. N., Battilocchio, C., Hawkins, J. M., & Ley, S. V. (2015). A Versatile Room‐Temperature Route to Di‐ and Trisubstituted Allenes Using Flow‐Generated Diazo Compounds. Angewandte Chemie, 127(27), 8031–8034. https://doi.org/10.1002/ange.201501538
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