Current Perspectives on Maternal Influenza Immunization

Abstract

Purpose of Review: Pregnant women and young infants are more likely to experience severe complications associated with influenza infection and are at increased risk of hospitalization. Influenza vaccination during pregnancy produces antibodies which protect the mother against infection, and due to transplacental transfer of maternal antibodies before birth, it also protects the infant in the first few months of life. Recent Findings: In many countries, influenza vaccination is recommended during pregnancy to protect mothers and their infants. In fact, influenza vaccine is the most widely used vaccine in pregnancy globally. When administered during pregnancy, the vaccine has been shown to be safe and effective for both mothers and their infants. Despite the health benefits, acceptance of influenza vaccine is low during pregnancy, indicating many women and infants are not protected against influenza. Summary: Concerted efforts are needed globally to improve the proportion of women and young infants who receive the health benefits of influenza vaccination.