A Phosphine-mediated conversion of azides into diazo compounds

Abstract

N2 the mild: Diazo compounds are extremely versatile intermediates for synthetic organic chemistry, but their synthesis can be challenging in the presence of delicate functional groups. The Staudinger ligation has inspired a mild method for the conversion of a broad range of azides into their diazo compound derivatives through an acyl triazene intermediate. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.