Functionalized carbon nanotubes for gene biodelivery

Abstract

The principles of non-covalent functionalization of carbon nanotubes will be described. The abilities of these biomolecules to solubilize carbon nanotubes and bind DNA will be also compared. Approaches for using functionalized carbon nanotubes to deliver genes to target cells and associated problems will be described. Evidence pertaining to the mechanism of entry of nucleic acid-loaded carbon nanotubes into mammalian cells will be also presented.