Invasive pulmonary aspergillosis due to Aspergillus terreus: 12-year experience and review of the literature

164Citations
Citations of this article
34Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

A 12-year retrospective analysis was done to identify and evaluate in detail cases of invasive pulmonary aspergillosis (IPA) caused by Aspergillus terreus. We identified 13 A. terreus infections among 133 total cases of confirmed invasive aspergillosis; 11 were IPA and 2 were primary peritoneal infections. Of the 11 patients with IPA, 7 developed neutropenia during hospitalization, and the remaining four were receiving immunosuppressive agents. Ten patients with IPA died; one liver transplantation patient without neutropenia survived after treatment with amphotericin B, itraconazole, and a pulmonary lobectomy. Six patients developed disseminated disease, with the heart the most common extrapulmonary site identified (four patients). These cases demonstrate that IPA caused by A. terreus rapidly progresses in immunocompromised patients receiving amphotericin B and illustrate the need for sensitive diagnostic tests and more effective antifungal agents.

Cite

CITATION STYLE

APA

Iwen, P. C., Rupp, M. E., Langnas, A. N., Reed, E. C., & Hinrichs, S. H. (1998). Invasive pulmonary aspergillosis due to Aspergillus terreus: 12-year experience and review of the literature. Clinical Infectious Diseases, 26(5), 1092–1097. https://doi.org/10.1086/520297

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free