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Synthesis of a photoresponsive alpha-dideoxyuridine triphosphate derivative

Nucleic acids symposium series (2004) (2008) (52) 293-294
DOI: 10.1093/nass/nrn148
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Abstract

The synthesis of a photoresponsive alpha-5-cyanovinyl- 2',3'-dideoxyuridine-5'-triphosphate (alpha dd(C)UTP) is described. A one-pot enzymatic synthesis of photoresponsive alpha-5-cyanovinyl-2',3'-dideoxyuridine (alpha dd(C)U) labeled ODNs with terminal deoxynucleotideyl transferase (TdT) would be a powerful tool for the development of modified long-chain DNA and branched DNA unable to be prepared by DNA synthesizer or enzymatic ligation.

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APA

Nitta, Y., Ogino, M., Yoshimura, Y., & Fujimoto, K. (2008). Synthesis of a photoresponsive alpha-dideoxyuridine triphosphate derivative. Nucleic Acids Symposium Series (2004), (52), 293–294. https://doi.org/10.1093/nass/nrn148

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