Abstract
It has recently been found that human hepatocellular carcinoma (HCC) preferentially takes up indocyanine green (ICG) in the clinical setting. We assessed the effectiveness of photodynamic therapy (PDT) using ICG and near-infrared (NIR) laser for HCC. HuH-7 (a well-differentiated human HCC) cell line was transplanted subcutaneously into mice. Mice were divided into groups: ICG administration only (ICG+ NIRa) and ICG and NIR laser exposure (ICG+ NIR+) at day 0. Mean tumor volume was significantly different between the ICG+ NIR+ group and the ICG+ NIR' group by day 9 (p <0.01). PDT suppressed HuH-7 human HCC cell line tumor growth.
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CITATION STYLE
Kaneko, J., Inagaki, Y., Ishizawa, T., & Kokudo, N. (2015). Near-Infrared laser photodynamic therapy for human hepatocellular carcinoma cell line tumor with indocyanine green fluorescence. In Fluorescence Imaging for Surgeons: Concepts and Applications (pp. 185–193). Springer International Publishing. https://doi.org/10.1007/978-3-319-15678-1_19
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