Breakup feared after filamin leaves GPIb

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Abstract

In this issue of Blood, Cranmer and colleagues demonstrate that the linkage between the cytoskeletal protein filamin A and the platelet receptor glycoprotein (GP) Ibα provides structural integrity to the plasmamembrane during platelet adhesion to von Willebrand factor (VWF) under high shear.

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Berny-Lang, M. A., & McCarty, O. J. T. (2011). Breakup feared after filamin leaves GPIb. Blood, 117(9), 2564–2565. https://doi.org/10.1182/blood-2011-01-327296

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