Chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq) is a new technology to map protein-DNA interactions in a genome. The genome-wide transcription factor binding site and chromatin modification data produced by ChIP-seq provide invaluable information for studying gene regulation. This chapter reviews basic characteristics of ChIP-seq data and introduces a computational procedure to identify protein-DNA interactions from ChIP-seq experiments.
CITATION STYLE
Ji, H. (2010). Computational analysis of ChIP-seq data. Methods in Molecular Biology (Clifton, N.J.), 674, 143–159. https://doi.org/10.1007/978-1-60761-854-6_9
Mendeley helps you to discover research relevant for your work.