Antibacterial Activity of Bisanthraquinone (+)-1,1’-Bislunatin

  • PRAPTIWI P
  • JAMAL Y
  • FATHONI A
  • et al.
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Abstract

Endophytic fungi has been known as a source of biologically active compunds with a broad sprectrum of activities. One of the endophytic fungi isolated from young stem of gambier plant ( Uncaria gambier Roxb.:Rubiaceae), Diaporthe sp. GNBP-10, produced (+)-1,1’-bislunatin when cultivated on potato dextrose agar (PDA). (+)-1,1’-Bislunatin showed moderate antibacterial activity against 7 bacteria ( Bacillus subtilis , Staphylococcus aureus , Escherichia coli , Micrococcus luteus , Shigella flexneri , Proteus vulgaris , and P. mirabilis ) with MIC value in the range of 32-64 µg mL -1 . The wall disruption and morphological changes in the cells affected by exposure of (+)-1,1’-bislunatin are also discussed in this article.

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APA

PRAPTIWI, P., JAMAL, Y., FATHONI, A., NURKANTO, A., & AGUSTA, A. (2013). Antibacterial Activity of Bisanthraquinone (+)-1,1’-Bislunatin. Microbiology Indonesia, 7(4), 159–166. https://doi.org/10.5454/mi.7.4.4

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