Major histocompatibility complex differentiation in Sacramento River chinook salmon

49Citations
Citations of this article
62Readers
Mendeley users who have this article in their library.
Get full text

Abstract

The chinook salmon of the Sacramento River, California, have been reduced to a fraction of their former abundance because of human impact and use of the river system. Here we examine the genetic variation at a major histocompatibility complex class II exon in the four Sacramento chinook salmon runs. Examination of the alleles found in these and other chinook salmon revealed nucleotide patterns consistent with selection for amino acid replacement at the putative antigen-binding sites. We found a significant amount of variation in each of the runs, including the federally endangered winter run. All of the samples were in Hardy-Weinberg proportions. A significant amount of genetic differentiation between runs was revealed by several measures of differentiation. Winter run was the most genetically divergent, while the spring, late-fall, and fall runs were less differentiated.

Cite

CITATION STYLE

APA

Kim, T. J., Parker, K. M., & Hedrick, P. W. (1999). Major histocompatibility complex differentiation in Sacramento River chinook salmon. Genetics, 151(3), 1115–1122. https://doi.org/10.1093/genetics/151.3.1115

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free