UDP-GlcNAc: BetaGal beta-1,3-NAcetylglucosaminyltransferase 4 (B3GNT4)

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Abstract

β1,3-N-Acetylglucosaminyltransferase (β3GnT) enzymes synthesize a unique carbohydrate structure known as polylactosamine (poly-N-acetyllactosamine). Polylactosamines are carried on N- and O-glycans and glycolipids. Polylactosamine units are considered as integral components serving as a fundamental structure and backbone for carbohydrate assemblies (Fig. 28.1).

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Togayachi, A., & Narimatsu, H. (2014). UDP-GlcNAc: BetaGal beta-1,3-NAcetylglucosaminyltransferase 4 (B3GNT4). In Handbook of Glycosyltransferases and Related Genes, Second Edition (Vol. 1, pp. 303–310). Springer Japan. https://doi.org/10.1007/978-4-431-54240-7_90

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