The roles of p38MAPK and caspase-3 in DADS-induced apoptosis in human HepG2 cells

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Abstract

The roles of p38MAPK and caspase-3 in DADS-induced apoptosis in human HepG2 cells were investigated. After the human HepG2 cells were treated with DADS, the cell viability, apoptosis and the activity changes of p38MAPK and caspase-3 were measured. The results indicated that DADS can activate p38MAPK and caspase-3. The results showed that p38MAPK and caspase-3 are involved in the process of DADS-induced apoptosis in human HepG2 cells and interact with each other.

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Ji, C., Ma, H., & Ren, F. (2010). The roles of p38MAPK and caspase-3 in DADS-induced apoptosis in human HepG2 cells. Archives of Biological Sciences, 62(2), 245–248. https://doi.org/10.2298/ABS1002245C

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