A Review of Polymorphism and the Amorphous State in the Formulation Strategy of Medicines and Marketed Drugs

Abstract

The different sold physical form of a medicine can affect its formulation and biological activity greatly. For such reasons, modern pharmaceuticals need to pass through extensive solid-state   evaluation. Within the recent year, pharmaceutical research became more and more aware with different solid-state as amorphous form, polymorphic salts and co crystals.  This review is the short outline for the different solid states giving specific examples for different marketed pharmaceutical products that had to pass through solid-state perforation.