Adecuación del protocolo de profilaxis antibiótica en las apendicectomías de población infantil

Abstract

Objective: To assess compliance of antibiotic prophylaxis in surgery for acute appendicitis in children and its effect on surgical site infection. Methods: We carried out a prospective cohort study to evaluate compliance of antibiotic prophylaxis in appen- dectomies in children. An assessment of the level of compliance with prophylaxis was made, as well as the causes of non-com- pliance. The effect of non-compliance of antibiotic prophylaxis on the incidence of surgical site infection was studied with the adjusted relative risk (RR) with a backstep logistic regression model. Results: The study included a total of 412 patients. Antibiotic prophylaxis was indicated in 348 patients, and administered in 95.7% of cases, with an overall protocol compliance of 90.7%. The principal cause of non-compliance was time of initiation. Cumulative incidence of surgical site infection was 2.7%. No relationship was found between inadequate prophylaxis compliance and infection (RR: 1.01; 95% confidence in- terval: 0.95-1.11; p = 0.61). Conclusions: Compliance of antibiotic prophylaxis was high, but could be improved. No relations- hip