Abstract
Comparing OKT3 and antithymocyte globulin (ATG) in a prospective study, the dosage difference in regard to body weight (ATG: dependent on body weight/OKT3: independent) does not introduce any obvious source of mistake concerning clinical effectiveness or side effects. One explanation for the lack of influence of body weight may be the high effectiveness of 5 mg of OKT3, reaching a maximal effect even with lower plasma levels in heavier patients. We wonder, therefore, whether the OKT3 dosage could be lowered.
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CITATION STYLE
Bachofen, M., Bock, H., Landmann, J., Thiel, G., Gallati, H., & Pracht, I. (1992). Dosage of OKT3 independent of body weight: a mistake? In Transplant International Official Journal of the European Society for Organ Transplantation (pp. 473–475). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-77423-2_138
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