Classification of primary bone lesions

Abstract

Primary bone tumors are classified on the base of their histological differentiation, as reported in the following table. Thay are divided into “benign” (with a limited capacity of local recurrence), “intermediate” (locally aggressive: local recurrence, also in a destructive way; rarely metastasizing: as above also with possible distant metastasis in occasional cases, not predictable on the basis of the morphology), and “malignant,” the latter furtherly divided into low-grade and high-grade malignant.