Galactoxylomannan does not exhibit cross-reactivity in the platelia Aspergillus enzyme immunoassay

Abstract

Given the recent report of a false-positive result in the Platelia Aspergillus enzyme immunoassay in a patient with cryptococcosis and in yeast extracts and purified galactoxylomannan of Cryptococcus neoformans, we evaluated culture extracts, purified polysaccharides, clinical specimens, and specimens from animals following experimental infection. Our results revealed no cross-reactions. Copyright © 2007, American Society for Microbiology. All Rights Reserved.