Meta-analysis in a Nutshell

  • Cleophas T
  • Zwinderman A
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Abstract

A meta-analysis is a systematic review with pooled outcome data. The current chapter gives a summary of methods for the purpose. Four scientific rules and three pitfalls are reviewed. The main benefit of meta-analysis is that it provides a pooled outcome with increased precision. The main criticisms are that so far they were not good at predicting subsequent large trials, and at predicting serious adverse effects of medicines.

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Cleophas, T. J., & Zwinderman, A. H. (2017). Meta-analysis in a Nutshell. In Modern Meta-Analysis (pp. 1–22). Springer International Publishing. https://doi.org/10.1007/978-3-319-55895-0_1

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