Molecular calculations and thermodynamical considerations on the solubility enhancement of triflumizole by cyclodextrin complexation

Abstract

Complexation of pesticides (fungicides, herbicides, insecticides, etc.) with cyclodextrins results in advantageous modifications of their properties like e.g. enhanced solubility and therefore a better activity combined with a reduced application concentration. The activity of the fungicide Triflumizole encapsulated in β-cyclodextrin was investigated and thermodynamical parameters of the association process were determined.