Considerations on Chlamydia trachomatis disease expression

Abstract

Chlamydia disease expression is the result of complex molecular and cellular interactions between the host and a pathogen which appears to have been sculpted by evolutionary forces. Recent genomic, immunologic, and epidemiologic findings are reviewed. A synthesis is offered which suggests that Chlamydia disease expression results from persistent infection and host immune responses. © 2008 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.